Hypothetical membrane mechanisms in essential tremor

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Membrane Mechanisms of Tremor

A number of neurological and psychogenic disorders present with tremor. In some, there is a known structural abnormality, while in others the pathophysiology is unknown. For example, the scarcity of a neurotransmitter from presynaptic neuronal degeneration causes tremor in degenerative cerebellar or basal ganglia disorders (Jankovic and Tolosa 2007 ) . Instability of the brainstem neural integr...

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Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor

BACKGROUND Harmaline and harmine are tremorigenic β-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature. This drug-induced action tremor has been proposed as a model of essential tremor. Here we review what is known about harmaline tremor. METHODS Using the terms harmaline and harmine on PubMed, we searched f...

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Tremor-correlated cortical activity in essential tremor.

BACKGROUND In patients with parkinsonian resting tremor, tremor-correlated activity in the contralateral sensorimotor cortex has been studied by both magnetoencephalography (MEG) and electroencephalography (EEG). In essential tremor, MEG failed to detect cortical involvement. The objective of this study was to investigate whether EEG recording can reveal tremor-correlated cortical activity in p...

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Tremor in a Bassoonist: Tremor in Dystonia or Essential Tremor?

JMD Dear Editor, Tremor is a common clinical feature in dystonia. It can be seen in both affected and unaffected body parts in patients with dystonia. Clinically, it may not be easily distinguishable from essential tremor, currently defined as a bilateral, largely symmetric postural or kinetic tremor involving the hands and forearms that is visible and persistent, with an associated or isolated...

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Review Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor

Background: Harmaline and harmine are tremorigenic b-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature. This drug-induced action tremor has been proposed as a model of essential tremor. Here we review what is known about harmaline tremor. Methods: Using the terms harmaline and harmine on PubMed, we searched f...

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ژورنال

عنوان ژورنال: Journal of Translational Medicine

سال: 2008

ISSN: 1479-5876

DOI: 10.1186/1479-5876-6-68